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Cognito Therapeutics has developed a non-invasive neuromodulation headset that uses synchronized light and sound stimulation to evoke gamma wave activity in the brain. In a Phase 2 trial, daily use of the device slowed cognitive and functional decline by over 80% compared to placebo, with additional evidence of preserved or increased white matter volume. No serious adverse events were reported. The pivotal Phase 3 trial is currently enrolling patients[1][2][3].
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