Ownership
Private
Employees
~8
Therapeutic Areas
Ophthalmology
Stage
Phase 2
Preclinical
Phase 1
Phase 2
Phase 3
Approved
Modalities
Antisense oligonucleotides

Amber Ophthalmics General Information

Amber Ophthalmics’ lead candidate Nexagon (lufepirsen ophthalmic gel) has shown promising results in a Phase 2 trial for PCED, with 67% of treated patients achieving complete corneal epithelial recovery versus 27% on placebo. The ongoing NEXPEDE‑1 study is a randomized, double-masked, vehicle-controlled Phase 2/3 trial evaluating two concentrations of Nexagon for PCED. The company’s approach leverages an unmodified antisense oligonucleotide targeting connexin43 to restore ocular homeostasis and promote healing in rare anterior segment eye diseases.

Contact Information

Primary Industry
Biotech
Corporate Office
San Diego, California
United States

Drug Pipeline

lufepirsen
Phase 2/3
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Drug Asset 2
Phase X
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Drug Asset 3
Phase X
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Key Partnerships

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Amber Ophthalmics Funding

No funding data available

Early Stage VC (Series A)04-Jun-2020$38MCompletedPhase 1
Seed Round12-Feb-2019$8.5MCompletedStartup

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Amber Ophthalmics Financial Metrics