Company intelligence / Profile preview
Aravive, Inc.
Houston, Texas, United Statesaravive.com ↗
- Ownership
- Public · ARAV
- Development stage
- Other
01
Overview
Aravive was a clinical-stage biopharmaceutical company focused on developing transformative treatments for life-threatening diseases such as cancer and fibrosis. Its lead candidate, batiraxcept (AVB-S6/S6–500), an ultrahigh-affinity decoy protein targeting the GAS6/AXL pathway, reached Phase III trials in platinum-resistant recurrent ovarian cancer but failed to show efficacy over standard of care. Other programs included early-phase studies in clear cell renal cell carcinoma and pancreatic adenocarcinoma. The company has faced significant setbacks following the failure of its pivotal trial and has limited cash runway[7][9].
- Therapeutic areas
- OncologyCardiovascular
- Modalities
- Recombinant fusion proteins (decoy proteins)Monoclonal antibodies (in partnership/licensing context)Antibody fusion proteins
- Industry
- Biotech
02
Drug pipeline
1 asset03
Partnerships
WuXi Biologics – collaboration to develop bispecific antibodies targeting oncology/fibrosis[1]3D Medicines – license agreement for batiraxcept development/commercialization in China region[1]
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