ORKA-001
Pre-clinical- Indications
- Psoriasis
Company intelligence / Profile preview
ARCA biopharma, Inc.
Westminster, Colorado, USAorukatx.com ↗
- Ownership
- Public · ABIO
- Development stage
- Preclinical
01
Overview
ARCA biopharma was a clinical-stage company focused on precision medicine approaches for cardiovascular disease. Its lead program Gencaro showed mixed results in a Phase IIb trial for atrial fibrillation but did not meet superiority endpoints. The company also advanced rNAPc2 as a novel anticoagulant therapy targeting COVID-related coagulopathy into late-stage clinical trials. In April 2024, ARCA announced a merger with Oruka Therapeutics to form a new entity focused on advancing best-in-class biologic therapies—specifically monoclonal antibodies targeting IL‑23p19 and IL‑17A/F—for chronic skin diseases such as psoriasis. The combined company will operate under the name Oruka Therapeutics.[9][6][4]
- Therapeutic areas
- HematologyImmunologyCardiovascularInfectious Diseases
- Modalities
- Small molecules (e.g., Gencaro/bucindolol hydrochloride)Protein therapeutics (e.g., rNAPc2/AB201)Monoclonal antibodies (in pipeline post-merger with Oruka Therapeutics)[5][4]DNA vaccine and therapeutic vaccine (historically in pipeline)[5]
- Industry
- Biotech
02
Drug pipeline
3 assets2 more assets in the full pipeline.
Request access →03
Partnerships
Post-merger financing led by Fairmount and Venrock Healthcare Capital Partners with participation from RTW Investments, Access Biotechnology, Commodore Capital, Deep Track Capital, Perceptive Advisors, Blackstone Multi‐Asset Investing, Avidity Partners etc.[4]
04
Financials
- Market cap
- $34.8M
- Total revenue
- $0
- Enterprise value
- $-836.2M
Beyond the preview
Go deeper on ARCA biopharma, Inc..
Explore clinical development, deal activity, and the competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow clinical development from trial design and recruitment through results.
- Trial phase
- Status
- Readouts
Licensing & deals
Full profile accessExplore licensing agreements, acquisitions, and the assets behind each deal.
- Partners
- Deal terms
- Milestones
Funding history
Full profile accessTrace financing activity and the investors behind a company’s development.
- Funding rounds
- Investors
- Capital raised
Competitive landscape
Full profile accessCompare peer pipelines by target, modality, and therapeutic area.
- Peer companies
- Targets
- Pipeline overlap
Technologies & patents
Full profile accessExplore technology platforms and the patent landscape around relevant assets.
- Platforms
- Patents
- Assignees
Research & analysis
Full profile accessConnect company news and source material to the questions you’re investigating.
- Company news
- Sources
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ARCA biopharma, Inc..