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SD‑809 (deutetrabenazine), a VMAT2 inhibitor developed using deuterium chemistry, showed promise in pivotal Phase 2/3 trials for tardive dyskinesia and Huntington's chorea with improved safety and dosing profile compared to existing therapies. Topline data from key trials were expected around mid‑2015[6][9]. The drug has been commercialized under the brand name Austedo by Teva post-acquisition.
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