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Ayerst, McKenna & Harrison was a prominent Canadian pharmaceutical company founded in 1924 in Montreal. The company achieved global recognition for its pioneering work in endocrinology, specifically the development of Premarin, a conjugated estrogen therapy derived from the urine of pregnant mares. Premarin became one of the most successful and widely prescribed treatments for menopausal symptoms in medical history. The company was acquired by American Home Products in 1943 and was later merged with Wyeth to form Wyeth-Ayerst Laboratories, eventually becoming part of Pfizer.
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