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Combangio, Inc.

Ownership: Public · KALA
Development stage: Phase 1

Overview

KPI-012 showed positive safety and efficacy signals in a Phase 1b trial where seven out of eight patients treated twice daily improved; six achieved complete corneal healing within weeks. The treatment was well tolerated with no safety issues reported. A $15 million grant from California Institute for Regenerative Medicine supports ongoing Phase 2b CHASE trial evaluating two doses versus vehicle control with topline data expected Q1 2024[1][2][3][4][6].

Therapeutic areas: Ophthalmology
Modalities: Regenerative biotherapies based on mesenchymal stem cell secretomes (MSC-S)Biologics-based investigational therapiesSecretome therapy derived from bone marrow MSCs
Industry: Biotech

Drug pipeline

1 asset

KPI-012

Phase 1

Indications: Persistent corneal epithelial defect, Rare ocular surface diseases

Partnerships

California Institute for Regenerative Medicine funding partnership ($15M grant)

Financials

Market cap: $10.9M
Total revenue: $0
Enterprise value: $3.7M

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