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Cyclacel is a clinical-stage biopharmaceutical company developing small molecule drugs targeting cell cycle control mechanisms in cancer. Its lead program, fadraciclib (CDK2/9 inhibitor), is in mid-stage clinical trials with encouraging early safety and efficacy data in biomarker-selected patients with advanced solid tumors. Plogosertib (PLK1 inhibitor) is also in mid-stage development. The pipeline includes additional assets at earlier stages or discontinued due to trial results.
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