OB756
NDA- Indications
- Not specified
Company intelligence / Profile preview
Their investigative JAK2 inhibitor OB756 (bonretinib) demonstrated favorable tolerability and meaningful clinical activity in Chinese patients with myelofibrosis who had no prior exposure to JAK inhibition. In a Phase 1/2 study, 54.5% of evaluable patients achieved a spleen volume reduction of at least 35% at the end of cycle 6, with no dose-limiting toxicities reported[9].
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