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Ho'ola Therapeutics owns two advanced oncology programs acquired from Oncternal Therapeutics: zilovertamab, a monoclonal antibody that reached Phase 3, and ONCT-808, a CAR-T therapy targeting ROR1. While zilovertamab's Phase 3 trial under Oncternal was ended prematurely due to commercial challenges, ONCT-808 had reached clinical testing but was paused following a safety event. Both programs are now positioned for further development under Ho'ola Therapeutics.[1][2][3][4][5][8]
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