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HSHS St. Elizabeth's Hospital is a nonprofit, faith-based general acute care hospital in O'Fallon, Illinois and a member of Hospital Sisters Health System. The hospital provides commercial-stage healthcare services rather than a drug development pipeline, with inpatient and outpatient care across heart care, cancer care, emergency medicine, surgery, imaging, infusion, orthopedics, women’s health, stroke care and other core hospital service lines. It operates as a regional medical center serving south-central and Metro East Illinois and emphasizes patient-centered care supported by clinical technology and multispecialty services. The organization is actively expanding its campus and care capacity, including emergency, inpatient, outpatient surgery and imaging infrastructure.
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