Interventional & Surgical Innovations

Interventional & Surgical Innovations (ISI) was a venture-funded medical device incubator founded in 2007 by Peter Hinchliffe and Trevi Health Ventures. Based in Campbell Hall, New York, the company specialized in accelerating the development of advanced technologies for general and cardiovascular surgery. Its portfolio included site-specific drug delivery systems, minimally invasive surgical instruments, and vascular implants such as inferior vena cava (IVC) filters and prosthetic venous valves. ISI operated by identifying promising early-stage technologies, providing engineering and clinical expertise, and spinning out successful ventures like Deep Vein Medical. The company also expanded its capabilities through the acquisition of Advantis Medical, focusing on high-performance surgical tools.