Company intelligence / Profile preview

Krystal Biotech, Inc.

Pittsburgh, Pennsylvania, United Stateskrystalbio.gcs-web.com ↗
Ownership
Public · KRYS
Development stage
Commercial
01

Overview

Krystal Biotech has received FDA approval for VYJUVEK (beremagene geperpavec-svdt), the first redosable gene therapy for treating dystrophic epidermolysis bullosa. The company reported strong Q4 2024 results with revenues increasing 116% to $91.1 million and full-year revenues growing 473% to $290.5 million. VYJUVEK achieved a 95% gross margin in Q4 with over 510 reimbursement approvals in the U.S. The company also received European Commission approval for VYJUVEK in April 2025. Their KB707 oncology program showed a 27% objective response rate in lung cancer patients[6][9].

Therapeutic areas
PulmonologyOphthalmologyDermatologyOncologyRare Diseases
Modalities
Gene therapyRedosable gene therapyHSV-1-based vector technology
Industry
Biotech
02

Drug pipeline

14 assets

beremagene geperpavec

Approved

13 more assets in the full pipeline.

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03

Financials

Market cap
$10.2B
Total revenue
$119.2M
Enterprise value
$9.3B

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