Company intelligence / Profile preview
Krystal Biotech, Inc.
Pittsburgh, Pennsylvania, United Stateskrystalbio.com ↗
- Ownership
- Public · KRYS
- Development stage
- Other
01
Overview
Krystal Biotech has received FDA approval for VYJUVEK (beremagene geperpavec-svdt), the first redosable gene therapy for treating dystrophic epidermolysis bullosa. The company reported strong Q4 2024 results with revenues increasing 116% to $91.1 million and full-year revenues growing 473% to $290.5 million. VYJUVEK achieved a 95% gross margin in Q4 with over 510 reimbursement approvals in the U.S. The company also received European Commission approval for VYJUVEK in April 2025. Their KB707 oncology program showed a 27% objective response rate in lung cancer patients[6][9].
- Therapeutic areas
- PulmonologyOphthalmologyDermatologyOncologyRare Diseases
- Modalities
- Gene therapyRedosable gene therapyHSV-1-based vector technology
- Industry
- Biotech
02
Drug pipeline
16 assets15 more assets in the full pipeline.
03
Financials
- Market cap
- $8.9B
- Total revenue
- $389.1M
- Enterprise value
- $8B
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