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Leading BioSciences, Inc.

Carlsbad, California, United Statesprnewswire.com ↗

Ownership: Private
Employees: ~7
Development stage: Phase 3

Overview

Leading BioSciences developed LB1148, an oral protease inhibitor designed to neutralize digestive enzymes released during surgery. The drug showed potential for improving GI recovery after major surgery and reducing postoperative complications such as abdominal adhesions. LB1148 received FDA Fast Track Designation for treating postoperative GI dysfunction in pediatric patients undergoing open-heart surgery. As of the merger with Seneca Biopharma in April 2021, the company was preparing for a Phase 2/3 study and anticipated reporting additional clinical data by year-end 2021

Therapeutic areas: Gastroenterology
Modalities: Small molecules (notably protease inhibitors)
Industry: Biotech

Drug pipeline

1 asset

LB1148

Phase 3

Indications: Post-surgical gastrointestinal dysfunction, Post-surgical adhesions, Neonatal open-heart surgery complications

Partnerships

Altium Capital led a $20M private placement concurrent with the merger

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