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Neoleukin Therapeutics, Inc.

Seattle, Washington, United Statesir.neurogene.com ↗

Ownership: Public · NLTX
Employees: ~30
Development stage: Phase 1

Overview

Neoleukin advanced the first-in-human clinical trial of a de novo designed cytokine mimetic, NL–201, targeting immune activation in cancer. The Phase 1 trial evaluated safety and preliminary efficacy both as monotherapy and in combination with pembrolizumab. Additional assets included preclinical-stage programs such as a SARS-CoV–2 decoy and an IL–2/IL–15 inhibitor. As of late 2023, the company ceased independent operations following its merger into Neurogene.

Therapeutic areas: OncologyImmunologyInfectious Diseases
Modalities: de novo protein therapeutics/protein engineeringcytokine mimeticsprotein decoys/inhibitors
Industry: Biotech

Drug pipeline

1 asset

NL-201

Preclinical

Indications: Cancer, Inflammatory disorders

Partnerships

Merck & Co., for supply/collaboration on pembrolizumab combination arm in the NL‐201 trial

Financials

Market cap: $8.2M
Total revenue: $0
Enterprise value: $-208.8M

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