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O&D BioTechnology is a South Korean biotechnology company specializing in the development of first-in-class small molecule therapeutics that target the O-GlcNAcylation pathway. The company's core technology focuses on inhibiting O-GlcNAc transferase (OGT), an enzyme that plays a critical role in protein post-translational modification and is often dysregulated in various cancers. Their lead research programs are directed toward treating colorectal cancer and other solid tumors by disrupting the metabolic adaptations of malignant cells. Founded as a spin-off from Chosun University, O&D BioTechnology is currently advancing its pipeline through pre-clinical validation and lead optimization.
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