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Privo Technologies, Inc.

Peabody, Massachusetts, United Statesprivotechnologies.com ↗
Ownership
Private
Development stage
Phase 3
01

Overview

Privo Technologies has developed a proprietary nanotechnology-based drug delivery platform for locoregional chemotherapy. Its lead product PRV111—a nanoengineered patch delivering cisplatin directly to tumor sites—has shown over a 70% reduction in tumor volume within one week with no dose-limiting toxicities in phase II trials for oral cavity cancer. The company’s CLN‑004 trial evaluates both PRV111 and intraoperative system PRV211 across leading US cancer centers. Both products aim to maximize efficacy while minimizing systemic toxicity. The company has received significant non-dilutive funding from NIH/NCI/FDA and plans pivotal global phase III studies targeting head & neck cancers.

Therapeutic areas
Oncology
Modalities
Nanoparticle-based drug delivery (cisplatin nanoparticles)Small molecules (cisplatin)Potential for proteins, biologics, nucleotides in future PRV derivatives
Industry
Biotech
02

Drug pipeline

4 assets

cisplatin nano-engineered intraoperative system

3

3 more assets in the full pipeline.

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03

Partnerships

Collaborations with FDANational Cancer Institute (NCI)National Institute of Dental and Craniofacial Research (NIDCR)major US academic medical centers participating as trial sites include University of Chicago MedicineCity of HopeMiami Cancer InstituteCleveland Clinic.

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