Providence Cancer Center, Earle A. Chiles Research Institute

The Earle A. Chiles Research Institute (EACRI), the research arm of the Providence Cancer Institute, is a leading center for cancer immunotherapy located in Portland, Oregon. Established in 1993, the institute specializes in translational research, moving discoveries from the bench to the bedside through an extensive clinical trials program. EACRI is particularly recognized for its work in T-cell biology, cytokine research, and the development of novel immunotherapies such as OX40 agonists and adoptive cell therapies. The institute collaborates extensively with global pharmaceutical companies and academic partners to advance the standard of care for various malignancies, including melanoma, lung, and breast cancers. With state-of-the-art GMP manufacturing facilities, EACRI is equipped to produce advanced cellular products for its clinical research initiatives.