Company intelligence / Profile preview

Spruce Biosciences, Inc.

South San Francisco, California, USAsprucebio.com ↗
Ownership
Public · SPRB
Employees
~50
Development stage
Other
01

Overview

The company has experienced mixed clinical results. Their lead candidate tildacerfont failed in two Phase 2 trials for CAH in 2024 and has been discontinued. They have acquired tralesinidase alfa (TA-ERT) for MPS IIIB, which has shown promising results in normalizing HS and HS-NRE levels over a five-year period, with plans to submit a BLA in 2026.

Therapeutic areas
PsychiatryEndocrinologyWomen's HealthRare DiseasesNeurology
Modalities
Small moleculesBiologicsEnzyme replacement therapy
Industry
Biotech
02

Drug pipeline

6 assets

tralesinidase alfa

4

5 more assets in the full pipeline.

03

Partnerships

HMNC (for MDD program)Kaken Pharmaceutical Co. Ltd.
04

Financials

Market cap
$122.7M
Total revenue
$0
Enterprise value
$34.1M

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