TG101348
Phase 2- Indications
- Myelofibrosis, Polycythemia vera, Leukemia, Lymphoma
Company intelligence / Profile preview
TargeGen developed oral small molecule kinase inhibitors targeting hematological malignancies and vascular disorders. Its lead asset TG101348 (fedratinib) was a JAK2 inhibitor for myeloproliferative diseases such as myelofibrosis. The company completed Phase I/II trials for this indication before being acquired by Sanofi in mid–2010. Other pipeline assets targeted various kinases but were discontinued or pending at the time of acquisition.
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