Company intelligence / Profile preview
Vaccinex, Inc.
- Ownership
- Public · VCNX
- Employees
- ~32
- Development stage
- Phase 2
Overview
Vaccinex's lead candidate pepinemab is a humanized monoclonal antibody targeting SEMA4D. In oncology trials such as KEYNOTE-B84 with Merck’s pembrolizumab for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC), interim data showed approximately double the objective response rate and progression-free survival in patients with low PD-L1 expression compared to historical controls. Pepinemab has also shown potential in neurodegenerative diseases like Alzheimer’s and Huntington’s disease. Final data from ongoing studies are expected at upcoming conferences.
- Therapeutic areas
- OncologyImmunologyNeurology
- Modalities
- Monoclonal antibodies (mAbs)Fusion proteinsAntibody discovery platforms
- Industry
- Biotech
Drug pipeline
5 assets4 more assets in the full pipeline.
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Financials
- Market cap
- $2.8M
- Total revenue
- $213K
- Enterprise value
- $1.7M
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