Company intelligence / Profile preview

Vaccinex, Inc.

Rochester, New York, United Statesvaccinex.com ↗
Ownership
Public · VCNX
Employees
~32
Development stage
Phase 2
01

Overview

Vaccinex's lead candidate pepinemab is a humanized monoclonal antibody targeting SEMA4D. In oncology trials such as KEYNOTE-B84 with Merck’s pembrolizumab for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC), interim data showed approximately double the objective response rate and progression-free survival in patients with low PD-L1 expression compared to historical controls. Pepinemab has also shown potential in neurodegenerative diseases like Alzheimer’s and Huntington’s disease. Final data from ongoing studies are expected at upcoming conferences.

Therapeutic areas
OncologyImmunologyNeurology
Modalities
Monoclonal antibodies (mAbs)Fusion proteinsAntibody discovery platforms
Industry
Biotech
02

Drug pipeline

5 assets

pepinemab

2

4 more assets in the full pipeline.

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03

Partnerships

Merck Sharp & Dohme Corp.Ares Trading S.A.Children’s Hospital of PhiladelphiaEmory UniversityHuntington Study GroupH. Lee Moffitt Cancer Center & Research Institute Inc.Catalent Pharma Solutions LLC.Surface Oncology Inc.
04

Financials

Market cap
$2.8M
Total revenue
$213K
Enterprise value
$1.7M

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