Company intelligence / Profile preview
Xi'an Yufan Biotechnology
Xi'an, Shaanxi, China
- Ownership
- Private
- Development stage
- Other
01
Overview
Xi'an Yufan Biotechnology is a clinical-stage biotech developing next-generation CAR-T therapies. Its lead program is a CRISPR-edited autologous CAR-T targeting CD19 with HPK1 knockout for hematological malignancies in Phase 1 trials. Early data presented at ASCO 2022 showed efficacy and adverse event profiles in precursor cell lymphoblastic leukemia/lymphoma and B-cell lymphoma patients[8]. The company also has preclinical programs targeting BCMA and other cancer antigens using its enhanced CAR-T platform.
- Therapeutic areas
- OncologyHematology
- Modalities
- CAR-T cell therapyGene therapySmall moleculeMonoclonal antibody (preclinical/discovery)
- Industry
- Biotech
02
Drug pipeline
2 assets1 more asset in the full pipeline.
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Partnerships
Abound Bio Inc. – multi-year agreement to develop next-generation enhanced CAR T-cells incorporating novel antibodies against up to ten cancer targets[4][5].
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