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Xi'an Yufan Biotechnology

Xi'an, Shaanxi, Chinayufanbio.com ↗
Ownership
Private
Development stage
Other
01

Overview

Xi'an Yufan Biotechnology is a clinical-stage biotech developing next-generation CAR-T therapies. Its lead program is a CRISPR-edited autologous CAR-T targeting CD19 with HPK1 knockout for hematological malignancies in Phase 1 trials. Early data presented at ASCO 2022 showed efficacy and adverse event profiles in precursor cell lymphoblastic leukemia/lymphoma and B-cell lymphoma patients[8]. The company also has preclinical programs targeting BCMA and other cancer antigens using its enhanced CAR-T platform.

Therapeutic areas
OncologyHematology
Modalities
CAR-T cell therapyGene therapySmall moleculeMonoclonal antibody (preclinical/discovery)
Industry
Biotech
02

Drug pipeline

2 assets

XYF19 CAR-T cell therapy

1

1 more asset in the full pipeline.

03

Partnerships

Abound Bio Inc. – multi-year agreement to develop next-generation enhanced CAR T-cells incorporating novel antibodies against up to ten cancer targets[4][5].

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