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(11R)-10-acetyl-11-(2,4-dichlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the benzodiazepine class of organic compounds[1][5]. Benzodiazepines are characterized by a benzene ring fused to a diazepine ring and are known for their diverse pharmacological activities such as anxiolytic (anti-anxiety), anticonvulsant (anti-seizure), and muscle relaxant properties[5]. The specific compound described here has not been approved for clinical use in any country and is classified as experimental with no reported indications or clinical trials beyond preclinical research phases[1]. Structural studies indicate it may have been investigated as an inhibitor of viral RNA polymerases such as HCV NS5B polymerase but there is no evidence of further development or therapeutic application[7].

Other names
10-acetyl-11-(2,4-dichlorophenyl)-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one(10R)-9-acetyl-10-(2,4-dichlorophenyl)-4-hydroxy-14,14-dimethyl-2,9-diazatricyclo[9.4.0.03^8]pentadeca‑1(11),3 ,5 ,7-tetraen‑12-one
02

Targets

RdRp (Coronavirus RNA-dependent RNA polymerase)

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