(2R)-2-phenyl-N-pyridin-4-ylbutanamide

(2R)-2-phenyl-N-pyridin-4-ylbutanamide is a synthetic small molecule belonging to the phenylacetamide class. It features a chiral center at the 2-position of the butanamide chain and contains both a phenyl group and a pyridine ring. The compound has been identified as an experimental molecule with no approved medical indications or clinical trial activity to date[1][2][3]. Notably, it has been studied as an inhibitor of sterol 14alpha-demethylase (CYP51), particularly in Mycobacterium tuberculosis, where it binds to the heme iron in CYP51's active site and may serve as a lead candidate for antifungal or antitubercular drug development[7]. No marketed products or established therapeutic uses are currently associated with this compound.

Other names

(2R)-2-phenyl-N-(pyridin-4-yl)butanamidealpha-ethyl-N-(4-pyridinyl)benzeneacetamideBenzeneacetamide, alpha-ethyl-N-(4-pyridinyl)-, (alphaR)