(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid

(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid is an experimental small molecule belonging to the class of biphenyl derivatives. It features a chiral center at the 2-position and contains both biphenylyl ether and phenyl groups attached to a propanoic acid backbone. The compound has been studied for its interaction with nuclear hormone receptors, particularly as a ligand for peroxisome proliferator–activated receptor gamma (PPAR-gamma), which plays roles in glucose metabolism and adipogenesis. Its precise mechanism of action and therapeutic applications remain under investigation; it is not approved for clinical use[1][3][4].

Other names

(2S)-3-phenyl-2-(4-phenylphenoxy)propanoic acid(S)-2-(Biphenyl-4-yloxy)-3-phenyl-propionic acidBenzenepropanoic acid, alpha-([1,1′-biphenyl]-4-yloxy)-, (alphaS)