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(2S)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol

Development stage
Preclinical
Lead developer
ChemDiv
Modality
Small Molecules
01

Overview

This compound is a small molecule inhibitor with the IUPAC name (2S)-2-{[3-(3‑aminophenyl)imidazo[1,2‑b]pyridazin‑6‑yl]amino}‑3‑methylbutan‑1‑ol. It belongs to the class of aromatic heteropolycyclic compounds and azoles. The compound has been identified as an experimental agent and is known to act as an inhibitor of serine/threonine-protein kinase haspin. Haspin is a nuclear protein kinase involved in chromatin regulation and cell cycle progression. Inhibition of haspin may have potential applications in cancer therapy due to its role in mitosis regulation. The compound’s development status appears limited to preclinical or early-stage research settings; there are no indications it has advanced into clinical trials or received regulatory approval for any indication.[1][2][7]

Other names
(2S)-2-{[3-(3-Aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol2-{[3-(3-Aminophenyl)imidazo[1,2-b]pyridazin-6-Yl]amino}-3-Methylbutan-1-OlDB08004DB-08004DB 08004
02

Targets

GSG2 (Germ cell associated 2, haspin)

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