(2S,4S,5R)-1-(4-tert-butylbenzoyl)-2-isobutyl-5-(1,3-thiazol-2-yl)pyrrolidine-2,4-dicarboxylic acid

This compound is a synthetic small molecule belonging to the class of N-acyl-alpha amino acids. It has been studied as an experimental agent and is not approved for clinical use. The molecule features a pyrrolidine core substituted with a tert-butylbenzoyl group at position 1, an isobutyl group at position 2, and a thiazol group at position 5. Its primary mechanism of action appears to be as an inhibitor of RNA-directed RNA polymerase (NS5b), which is essential for the replication of certain viruses such as hepatitis C virus[6][10]. There are no known approved indications or marketed products containing this compound.

Other names

(2S,4S,5R)-1-(4-tert-butylbenzoyl)-2-isobutyl-5-(1,3-thiazol-2-yl)pyrrolidine-2,4-dicarboxylic acid698 (PDB ligand code)