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(3AS,4R,9BR)-2,2-difluoro-4-(4-hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the class of organic compounds known as flavonoids—specifically a C-ring modified benzopyran scaffold. It acts as an experimental selective estrogen receptor modulator (SERM), with demonstrated binding affinity for both estrogen receptor alpha and beta. The compound has not been approved for clinical use and is primarily used in research settings to study estrogen receptor modulation[1][10][6].

Other names
(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-1,2,3-,3a-, 4-, 9b,-hexahydrocyclopenta[c]chromen-8-olBenzo[b]cyclopenta[d]pyran‑8‑ol 2 2‑difluoro‑1 2 3 3a 4 9b‑hexahydro‑4(4 hydroxyphenyl) (IUPAC/Index)
02

Targets

ESR2 (ERβ)ESR1 (ERα)

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