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(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the class of beta-carbolines—organic compounds containing a 9H-pyrido[3,4-b]indole moiety. It is catalogued as DrugBank ID DB08166 and is considered experimental with no current approved indications or clinical trial activity reported. The structure features a spiro-fused beta-carboline and piperidine ring system. Beta-carbolines are known for diverse pharmacological activities including interactions with various enzymes and receptors; however, for this specific compound the only identified protein target is serine/threonine-protein kinase pim-1 in humans. Its precise mechanism of action remains uncharacterized in public databases[1][3].

Other names
(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile
02

Targets

PIM1 (Proviral integration site for moloney murine leukemia virus kinase 1)

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