(6S)-N-[(2S,3R,6R,7R)-3-(Acetyloxymethyl)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]octan-7-yl]-6-[(2-aminoacetyl)amino]-7-hydroxy-7-oxoheptanimidate

This compound is a cephalosporin-related small molecule, identified in chemical databases as a derivative of the cephem nucleus (5-thia-1-azabicyclo[4.2.0]octane). It features an acetyloxymethyl group at the 3-position and a complex 7-position side chain containing a glycylamino-heptanoic acid moiety. Structurally similar to cephalosporin antibiotics, it is designed to interact with penicillin-binding proteins (PBPs), which are critical enzymes in bacterial peptidoglycan synthesis. By binding to these proteins, the molecule inhibits the cross-linking of the bacterial cell wall, leading to cell lysis. It is primarily documented as a research compound or ligand (e.g., PDB ligand G2A) used in crystallographic studies to map the active sites of enzymes like beta-lactamases or PBPs. No evidence exists for its development as a therapeutic agent or its use in clinical trials.

Other names

6-(glycylamino)-7-oxo-7-{[(2R,6R,7R)-2-carboxy-8-oxo-3-(acetyloxymethyl)-5-thia-1-azabicyclo[4.2.0]oct-7-yl]amino}heptanoic acid