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[11C]-NOP46

Development stage: Phase 1
Lead developer: Columbia University
Modality: Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration: Intravenous

Overview

[11C]-NOP46 is a novel experimental radioactive drug developed as a positron emission tomography (PET) radiotracer. It is designed for diagnostic imaging, specifically to visualize and identify the sources of chronic pain in the body by targeting specific pain pathways. Administered in microdoses, it is used in conjunction with PET/computed tomography (CT) scans to assess its safety and distribution within the body. The drug is currently undergoing early-phase clinical trials to understand its pharmacokinetics and potential in revolutionizing chronic pain diagnosis and management. Columbia University is a key institution involved in its development and clinical evaluation.

Other names: NOP46NOP-46NOP 46radiotracerradioactive drug

Targets

NOP (Nociceptin/orphanin FQ peptide receptor)

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