Drug intelligence / Profile preview

[11C]APP311

Development stage
Phase 1
Lead developer
Yale University
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

[11C]APP311 is a radiolabeled small molecule used as a positron emission tomography (PET) imaging agent. It is labeled with carbon-11, a short-lived positron-emitting isotope, and is designed for use in research and clinical studies to visualize specific molecular targets or physiological processes in vivo. The compound has the molecular formula C17H15F3N2O and an absolute stereochemistry at one center. As a radiopharmaceutical, its primary mechanism of action involves acting as a ligand that binds to specific biological targets, allowing their distribution and density to be imaged using PET technology. The exact biological target of [11C]APP311 is not specified in the available data; however, it functions as a radioligand for PET imaging applications[1]. Its development aligns with the broader use of carbon-11-labeled tracers for non-invasive imaging of metabolism, synaptic function, or receptor expression in tissues such as brain or heart[2][8].

Other names
99PJR3QL3Y

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