Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
[11C]CHDI-00485626
- Development stage
- Unknown
- Lead developer
- CHDI Foundation
- Modality
- Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
[11C]CHDI-00485626 is a Carbon-11 labeled radiopharmaceutical developed as a Positron Emission Tomography (PET) imaging agent. It is designed to selectively bind to mutant huntingtin (mHTT) protein aggregates in the brain. Huntington's disease is characterized by the expansion of CAG repeats in the HTT gene, leading to the production of mHTT, which aggregates and causes neurodegeneration. This tracer allows for the non-invasive quantification of mHTT load in vivo, serving as a critical biomarker for disease progression and the evaluation of huntingtin-lowering therapies in clinical trials. It was developed through a collaboration involving the CHDI Foundation.
- Other names
- [11C]CHDI-485626CHDI-485626CHDI485626CHDI 485626
02
Targets
mHTT (Mutant Huntingtin Protein)
Beyond the preview
Go deeper on [11C]CHDI-00485626.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on [11C]CHDI-00485626.