Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
[18F]DPA-714
- Development stage
- Unknown
- Lead developer
- Bayer
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Small Molecules
- Administration
- Intravenous
01
Overview
[18F]DPA-714 is a radioactive tracer used in Positron Emission Tomography (PET) imaging that specifically binds to the 18-kDa translocator protein (TSPO), formerly known as the peripheral benzodiazepine receptor. This radiotracer is designed to visualize neuroinflammation in the brain by targeting TSPO, which is expressed at higher levels in activated microglia during inflammatory processes. It has shown promise in clinical trials for imaging neuroinflammation in various neurological conditions including Alzheimer's disease, epilepsy, and autoimmune encephalitis.
- Other names
- N,N-diethyl-2-(2-(4-(2-[18F]-fluoroethoxy)phenyl)5,7-dimethylpyrazolo[1,5a]pyrimidin-3-yl)acetamide
02
Targets
TSPO (Translocator Protein (18 kDa))
Beyond the preview
Go deeper on [18F]DPA-714.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on [18F]DPA-714.