Drug intelligence / Profile preview

[18F]F-RESCA-RB14

Development stage
Phase 2
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Small Molecules
Administration
Intravenous
01

Overview

[18F]F-RESCA-RB14 is a radiopharmaceutical compound designed for positron emission tomography (PET) imaging. It utilizes the fluorine-18 isotope, which is well-suited for PET due to its favorable half-life and imaging properties. The RESCA chelator enables efficient and mild radiolabeling of peptides, proteins, or biologics with fluorine-18 via the Al[18F]F method. This approach allows rapid, one-step synthesis under Good Manufacturing Practices (GMP), making it suitable for clinical applications where high image resolution and centralized production are advantageous. The specific biological target or indication of RB14 is not detailed in available sources; however, compounds labeled with [18F] using RESCA are typically developed as molecular imaging agents to visualize specific targets in oncology or other disease areas[8].

Other names
[18F]F-RB14
02

Targets

ERBB2 (Erb-b2 receptor tyrosine kinase 2)

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