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[18F]MNI-952
- Development stage
- Phase 1
- Lead developer
- Invicro
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Small Molecules
- Administration
- Parenteral, Injection (intravenous)
01
Overview
[18F]MNI-952 is a radiopharmaceutical diagnostic agent developed as a positron emission tomography (PET) radioligand for imaging tau protein aggregates in the brain. It is designed to enhance PET imaging by selectively binding to microtubule-associated protein tau, which accumulates abnormally in neurodegenerative diseases such as Alzheimer's disease and progressive supranuclear palsy. The compound contains the radioactive isotope fluorine-18 ([^18F]), enabling visualization of tau pathology in vivo. Its primary use is investigational, aimed at aiding diagnosis and research into tauopathies by providing detailed images of tau distribution and burden within the central nervous system[1][2][4].
- Other names
- [18F]MNI 952[18F]UCB-K18F-UCB-K
02
Targets
MAPT (Microtubule-associated protein tau)
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