Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
[18F]PR04.MZ
- Development stage
- Unknown
- Lead developer
- Positronpharma
- Modality
- Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
[18F]PR04.MZ is a fluorine-18 labeled tropane derivative used as a positron emission tomography (PET) radiotracer for imaging the dopamine transporter (DAT). It is characterized by high affinity and selectivity for DAT, providing a more accurate assessment of presynaptic dopaminergic neuron density compared to earlier tracers. Clinical research has focused on its utility in the differential diagnosis of Parkinson's disease (PD) and atypical parkinsonian syndromes, such as progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), particularly within the first five years of symptom onset. Notably, it is capable of visualizing dopaminergic loss in the substantia nigra pars compacta (SNpc), a feature that distinguishes it from many other DAT ligands.
- Other names
- 18F-PR04.MZ
02
Targets
DAT (Dopamine plasma membrane transport protein)
Beyond the preview
Go deeper on [18F]PR04.MZ.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on [18F]PR04.MZ.