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[18F]scyllo-3

Development stage: Preclinical
Modality: Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics

Overview

[18F]scyllo-3 is a novel [18F]fluoro-inositol-based radiotracer, specifically synthesized in the scyllo-inositol configuration. It features a propyl linker bearing fluorine-18, which can be either O-alkylated or C-branched. This radiotracer is being developed as a Positron Emission Tomography (PET) imaging agent, with preliminary preclinical evaluation conducted in breast tumor-bearing mouse models to assess its potential for monitoring breast cancer.

Targets

Aβ (Amyloid-beta peptides and aggregates)

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