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[4-(3-aminomethyl-phenyl)-piperidin-1-yl]-(5-phenethyl-pyridin-3-yl)-methanone

Development stage
Unknown
Modality
Small Molecules
01

Overview

[4-(3-Aminomethyl-phenyl)-piperidin-1-YL]-(5-phentethyl-pyridin–3-YL)-methanone is an experimental small molecule belonging to the phenylpiperidine class. It has been studied as a ligand and inhibitor for human beta tryptase, a serine protease involved in allergic and inflammatory responses. Structural studies have shown it can bind to beta tryptase, potentially acting as a monomeric or dimeric inhibitor by bridging adjacent active sites of the enzyme. The compound has not been approved for any indication and remains at the experimental stage, with no clinical trials reported beyond preclinical research[1][2][4].

Other names
1-[3-(1-{[5-(2-phenylethyl)pyridin-3-yl]carbonyl}piperidin-4-yl)phenyl]methanamine
02

Targets

TPSB2 (Mast Cell Tryptase)

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