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[67Cu]Cu-rhPSMA-10.1
- Development stage
- Unknown
- Lead developer
- Clarity Pharmaceuticals
- Modality
- Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
[67Cu]Cu-rhPSMA-10.1 is a **radiohybrid prostate-specific membrane antigen (PSMA)-targeted radiopharmaceutical** labeled with copper-67, designed for targeted radionuclide therapy of PSMA-expressing tumors, such as prostate cancer and glioblastoma multiforme (GBM). It delivers cytotoxic radiation selectively to PSMA-positive cancer cells via the high-affinity PSMA-targeting ligand rhPSMA-10.1, enabling targeted destruction of malignant tissue while sparing healthy cells. Its theranostic potential is supported by PET-based dosimetry and SPECT imaging, and it is currently in early clinical/late preclinical evaluation[3][5][6].
- Other names
- [67Cu]Cu-rhPSMA-10.1
02
Targets
PSMA (Prostate-specific membrane antigen)
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