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[68Ga]Ga-CBT-001-2334
- Development stage
- Unknown
- Lead developer
- C-BIOMEX
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Peptides
- Administration
- Intravenous
01
Overview
[68Ga]Ga-CBT-001-2334 is a gallium-68 labeled peptide-based radiopharmaceutical targeting carbonic anhydrase IX (CAIX). Developed by C-Biomex in collaboration with the University of Texas MD Anderson Cancer Center, it is designed as a positron emission tomography (PET) imaging tracer for the detection and characterization of CAIX-expressing solid tumors, particularly clear cell renal cell carcinoma (ccRCC). The tracer consists of a proprietary CAIX-targeting peptide conjugated to a DOTA chelator, which is radiolabeled with gallium-68. It is intended to serve as a diagnostic companion to therapeutic radioligands targeting CAIX, such as [177Lu]Lu-CBT-001-2334.
- Other names
- 68Ga-CBT-001-2334
02
Targets
CA9 (Carbonic anhydrase IX)
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