(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine

(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine is a synthetic adenosine analog that functions as an inhibitor of S-Adenosylhomocysteine (AdoHcy) hydrolase. This enzyme plays a crucial role in regulating adenosylmethionine-dependent transmethylations by hydrolyzing AdoHcy into homocysteine and adenosine. The compound's unique binding mode to AdoHcy hydrolase has been characterized, involving interactions from two protein monomers and a catalytic water molecule. While primarily studied in a research context, its inhibitory action on AdoHcy hydrolase suggests potential relevance in conditions such as Hypermethioninemia and disorders related to methionine metabolism.