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1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Development stage
Unknown
Modality
Small Molecules
01

Overview

1-(1-methylethyl)-3-quinolin-6-yl‑1H‑pyrazolo[3,4‑d]pyrimidin‑4‑amine is an experimental small molecule compound containing a quinoline moiety fused to a pyrazolopyrimidine core. It has been studied as a potential inhibitor of the proto-oncogene tyrosine-protein kinase Src (SRC), which is involved in cell signaling pathways regulating proliferation and survival. The compound has not been approved for any indication and there are no reported clinical trials beyond preclinical or early research phases. Its mechanism of action is presumed to involve inhibition of SRC kinase activity based on structural similarity to other known SRC inhibitors and its listing as interacting with SRC in curated drug-target datasets[1][6].

Other names
1-isopropyl-3-(6-quinolyl)pyrazolo[3,4-d]pyrimidin-4-amine
02

Targets

SRC (Proto-oncogene tyrosine-protein kinase Src)

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