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1-[4-(aminomethyl)benzoyl]-5'-fluoro-1'H-spiro[piperidine-4,2'-quinazolin]-4'-amine
- Development stage
- Preclinical
- Modality
- Small Molecules
01
Overview
This compound is a synthetic small molecule belonging to the class of n-benzoylpiperidines. It is also known by the code name AR-C120011 and as ligand XXZ in structural biology databases. The molecule has been studied primarily as an experimental inhibitor of inducible nitric oxide synthase (iNOS or NOS2), with structural data available from murine iNOS-inhibitor complexes. There are no approved indications or clinical trials beyond preclinical/structural studies, and it is not approved for any therapeutic use[1][3][10].
- Other names
- 1-[4-(aminomethyl)benzoyl]-5'-fluoro-1'H-spiro[piperidine-4,2'-quinazolin]-4'-amine
02
Targets
NOS2 (Nitric Oxide Synthase 2)
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