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1-acetyl-4-(4-{4-[(2-ethoxyphenyl)thio]-3-nitrophenyl}pyridin-2-yl)piperazine
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
A synthetic small molecule with the formula C25H26N4O4S, 1-acetyl-4-(4-{4-[ (2‑ethoxyphenyl) thio ]‑3‑nitrophenyl } pyridin‑2‑‑ yl ) piperazine is an experimental compound. It has been studied as a potential allosteric inhibitor of integrin alpha-L/beta‑2 (LFA‑1), a cell adhesion molecule involved in immune cell trafficking and inflammation. The compound binds to the I-domain of LFA‑1, modulating its function and potentially inhibiting leukocyte adhesion. There are no approved clinical indications or marketed products containing this molecule[6][7][10].
- Other names
- 1-Acetyl-4-(4-{4-[(2-Ethoxyphenyl)Thio]-3-Nitrophenyl}Pyridin-2-Yl)Piperazine1-[4-(4-{4-[(2-Ethoxyphenyl)sulfanyl]-3-nitrophenyl}pyridin-2-yl)piperazin-1-yl]ethanone1-[4-(4-{4-[ (2-Ethoxyphenyl)sulfanyl ] -3-nitrophenyl } pyridin -2 - yl ) piperazin -1 - yl ] ethanone
02
Targets
LFA-1 (Integrin αLβ2)
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