2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate)

**Description:** 2'-deoxy-5-(hydroxymethyl)uridine 5'-(dihydrogen phosphate) is a synthetic pyrimidine nucleotide analog and a phosphorylated derivative of the nucleoside analog 2'-deoxyuridine. It features a hydroxymethyl group at the C‑5 position of the uracil base and a monophosphate group at the C‑5' position of the deoxyribose sugar[1][4][7]. This compound belongs to the class of pyrimidine deoxyribonucleoside monophosphates[2]. **Mechanism & Use:** It has been studied for its anticancer and antiviral activities as well as its use as a diagnostic biomarker for oxidative stress in mammalian cells. Its incorporation into DNA can serve as an indicator of cancer or cellular oxidative damage[1]. The compound is primarily used in research settings; there are no approved therapeutic indications.

Other names

5-hydroxymethyluridine-2'-deoxy-5'-monophosphate2′-Deoxy-5-(hydroxymethyl)uridine 5′-(dihydrogen phosphate)[(2R,3S,5R)-3-hydroxy-5-[5-(hydroxymethyl)-2,4-dioxopyrimidin-1-yl]oxolan-2-yl]methyl dihydrogen phosphatePhosphoric acid mono-[3-hydroxy-5-(5-hydroxymethyl-2,4-dioxo-pyrimidinyl)-tetrahydrofuran-2-methyl] ester