2'-deoxyuridine 5'-alpha,beta-imido-diphosphate

**Description:** 2'-deoxyuridine 5'-alpha,beta-imido-diphosphate is a synthetic nucleotide analog belonging to the class of pyrimidine 2’-deoxyribonucleosides. It is structurally related to deoxyuridine diphosphate but features an imido (NH) linkage between the alpha and beta phosphate groups that renders it non-hydrolyzable by most enzymes. This property makes it valuable as a biochemical probe in studies of nucleotide metabolism and enzyme mechanisms involving nucleotides. The compound has been investigated for its potential applications in antiviral and anticancer therapy due to its ability to act as a stable substrate or inhibitor for enzymes such as dUTPase[1][3]. Its primary use remains experimental in research settings.

Other names

2′-DEOXYURIDINE 5′-α,β-IMIDO-DIPHOSPHATE[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)amino]phosphonic acidC9H15N3O10P2 (chemical formula)