2,3-diphenyl-1H-indole-7-carboxylic acid

2,3-diphenyl-1H-indole-7-carboxylic acid is a synthetic small molecule belonging to the class of organic compounds known as indoles substituted at the 2 and 3 positions with phenyl groups and at the 7 position with a carboxylic acid group. It has been studied primarily as an experimental compound and is not approved for clinical use. The compound acts as an inhibitor of serine/threonine-protein kinase pim‑1 (PIM1), a proto-oncogene implicated in cell survival and proliferation pathways. Its inhibitory activity against PIM1 kinase suggests potential applications in diseases related to enzymatic dysregulation or cellular dysfunction[1][9][10]. No approved therapeutic indications or marketed products are associated with this molecule.

Other names

2,3-diphenyl-indole-7-carboxylic aciddiphenylindole carboxylic acid,37-Carboxy-2,3-diphenyl-1H-indole1H-Indole-7-carboxylic acid, 2,3-diphenyl-Acide 2,3-diphényl-1H-indole-7-carboxyliqueMFCD00572872MFCD-00572872MFCD 00572872