Drug intelligence / Profile preview

2,5-bis(4-(diethylamino)benzylidene)cyclopentanone

Development stage
Preclinical
Modality
Small Molecules
01

Overview

BDBC (2,5-bis(4-(diethylamino)benzylidene)cyclopentanone) is a chemical compound utilized as a key component in carrier-free core-shell nanodrugs, specifically BCNPs, designed for synergistic two-photon photodynamic therapy (PDT) in the treatment of cervical cancer. When co-assembled with curcumin, BDBC significantly contributes to a high singlet oxygen yield and demonstrates enhanced efficacy in inhibiting the proliferation of HeLa cells under 450/808 nm irradiation. This compound's role is crucial in the synergistic therapeutic approach for cancer.

02

Targets

^1O2 (Singlet oxygen)

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